Monday, 13 May 2024

Respiratory Evidence Update April 2024

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Respiratory Evidence Update

April 30th 2024
 

Contents

Leicester Publications
New & Noteworthy
East Midlands Evidence Repository
COVID-19 Updates
NICE Guidance
Cochrane Systematic Reviews
NIHR Signals
Other items of interest (including UpToDate & DynaMed)

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Leicester Publications

If any of your recently published papers are missing from this list, please let me know!
 

Defining the mechanism of galectin-3-mediated TGF-β1 activation and its role in lung fibrosis.
Calver JF, Parmar NR, Harris G, Lithgo RM, Stylianou P, Zetterberg FR, Gooptu B, Mackinnon AC, Carr SB, Borthwick LA, Scott DJ, Stewart ID, Slack RJ, Jenkins RG, John AE.

Biomarker Predictors of Clinical Efficacy of the Anti-IgE Biologic, Omalizumab, in Severe Asthma in Adults: Results of the SoMOSA Study.
Djukanović R, Brinkman P, Kolmert J, Gomez C, Schofield J, Brandsma J, Shapanis A, Skipp PJS, Postle A, Wheelock C, Dahlen SE, Sterk PJ, Brown T, Jackson DJ, Mansur A, Pavord I, Patel M, Brightling C, Siddiqui S, Bradding P, Sabroe I, Saralaya D, Chishimba L, Porter J, Robinson D, Fowler S, Howarth PH, Little L, Oliver T, Hill K, Stanton L, Allen A, Ellis D, Griffiths G, Harrison T, Akenroye A, Lasky-Su J, Heaney L, Chaudhuri R, Kurukulaaratchy R.

Development of Patient and Caregiver Conceptual Models Investigating the Health-Related Quality of Life Impacts of Malignant Pleural Mesothelioma.
Gibson AEJ, Ahmed W, Longworth L, Bennett B, Daumont M, Darlison L.

Airway remodelling in asthma and the epithelium: on the edge of a new era.
Varricchi G, Brightling CE, Grainge C, Lambrecht BN, Chanez P.

Changes in physical activity, sedentary behaviour and sleep following pulmonary rehabilitation: a systematic review and network meta-analysis.
Manifield J, Chaudhry Y, Singh SJ, Ward TJC, Whelan ME, Orme MW.
 

Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease.
Liew F, Efstathiou C, Fontanella S, Richardson M, Saunders R, Swieboda D, Sidhu JK, Ascough S, Moore SC, Mohamed N, Nunag J, King C, Leavy OC, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M, Harris VC, Houchen-Wolloff L, Greening NJ, Lone NI, Thorpe M, Thompson AAR, Rowland-Jones SL, Docherty AB, Chalmers JD, Ho LP, Horsley A, Raman B, Poinasamy K, Marks M, Kon OM, Howard LS, Wootton DG, Quint JK, de Silva TI, Ho A, Chiu C, Harrison EM, Greenhalf W, Baillie JK, Semple MG, Turtle L, Evans RA, Wain LV, Brightling C, Thwaites RS, Openshaw PJM; PHOSP-COVID collaborative group; ISARIC investigators.

Personalised Exercise-Rehabilitation FOR people with Multiple long-term conditions (PERFORM): protocol for a randomised feasibility trial.
Simpson SA, Evans RA, Gilbert HR, Branson A, Barber S, McIntosh E, Ahmed Z, Dean SG, Doherty PJ, Gardiner N, Greaves C, Daw P, Ibbotson T, Jani B, Jolly K, Mair F, Ormandy P, Smith S, Singh SJ, Taylor R.

Bronchoconstriction damages airway epithelia by crowding-induced excess cell extrusion.
Bagley DC, Russell T, Ortiz-Zapater E, Stinson S, Fox K, Redd PF, Joseph M, Deering-Rice C, Reilly C, Parsons M, Brightling C, Rosenblatt J.

The airway epithelium: an orchestrator of inflammation, a key structural barrier and a therapeutic target in severe asthma.
Russell RJ, Boulet LP, Brightling CE, Pavord ID, Porsbjerg C, Dorscheid D, Sverrild A.

Biomarkers Associated with Lung Function Decline and Dupilumab Response in Patients with Asthma.
Pavord ID, De Prado Gómez L, Brusselle G, Jackson DJ, Brightling CE, Papi A, Maspero JF, Rabe KF, Korn S, Zhang M, Soler X, Jacob-Nara JA, Hardin M; QUEST Lung Function Decline Study Group.

Phenotyping of Severe Asthma in the Era of Broad-Acting Anti-Asthma Biologics.
Bourdin A, Brusselle G, Couillard S, Fajt ML, Heaney LG, Israel E, McDowell PJ, Menzies-Gow A, Martin N, Mitchell PD, Petousi N, Quirce S, Schleich F, Pavord ID.

Evaluation of a COVID-19 fundamental nursing care guideline versus usual care: The COVID-NURSE cluster randomized controlled trial.
Richards DA, Bollen J, Jones B, Melendez-Torres GJ, Hulme C, Cockcroft E, Cook H, Cooper J, Creanor S, Cruickshank S, Dawe P, Doris F, Iles-Smith H, Kent M, Logan P, O'Connell A, Onysk J, Owens R, Quinn L, Rafferty AM, Romanczuk L, Russell AM, Shepherd M, Singh SJ, Sugg HVR, Coon JT, Tooze S, Warren FC, Whale B, Wootton S.

The Role of Multilevel Intercostal Nerve Block in Local Anesthetic Thoracoscopy.
Ajmal S, Johnstone S, Tufail M, Panchal RK.
 

Search PubMed for up to date Leicester Publications

Noteworthy research

Asthma   *   Lung Cancer   *   Interstitial Lung Disease   *   Cystic Fibrosis   *   COPD   *   Mesothelioma   *  Smoking   *  Tuberculosis   *   Artificial Intelligence   *   Other 


Asthma

Biologic agents licensed for severe asthma: a systematic review and meta-analysis of randomised controlled trials.

Acoustic biomarkers in asthma: a systematic review.


Lung Cancer

Is neoadjuvant immunotherapy necessary in patients with programmed death ligand 1 expression-negative resectable non-small cell lung cancer? A systematic review and meta-analysis.

Prognosis stratification of cancer patients treated with immune checkpoint inhibitors through lung immune prognostic index: a meta-analysis and systematic review.

Radial endobronchial ultrasound - guided bronchoscopy for the diagnosis of peripheral pulmonary lesions: A systematic review and meta-analysis of prospective trials.

Mortality burden of pre-treatment weight loss in patients with non-small-cell lung cancer: A systematic literature review and meta-analysis.

What is the role of physical exercise in the era of cancer prehabilitation? A systematic review.

Pretreatment quality of life and survival in patients with lung cancer: a systematic review and meta-analysis.



Interstitial Lung Disease

Clinical utility of the Borg dyspnoea score in 6-minute walk tests in interstitial lung disease: A systematic review.

The Role of Proton Pump Inhibitors in the Realm of Idiopathic Pulmonary Fibrosis and its Associated Comorbidities: A Systematic Review.



Cystic Fibrosis

A systematic review of animal and human data comparing the nasal potential difference test between cystic fibrosis and control.

The effect of respiratory muscle training on children and adolescents with cystic fibrosis: a systematic review and meta-analysis.



COPD

How to Enhance the Diagnosis of Early Stages of Chronic Obstructive Pulmonary Disease (COPD)? The Role of Mobile Spirometry in COPD Screening and Diagnosis-A Systematic Review.

Gait differences between COPD and healthy controls: systematic review and meta-analysis.

Modifiable risk factors that may be addressed in routine care to prevent progression to and extension of multimorbidity in people with COPD: a systematic literature review.

Chronic obstructive pulmonary disease as a risk factor for sarcopenia: A systematic review and meta-analysis.

Improvement of Lung Function by Micronutrient Supplementation in Patients with COPD: A Systematic Review and Meta-Analysis.

Treatment with systemic corticosteroid versus placebo for exacerbations of COPD: A systematic review and meta-analysis.

High-flow nasal cannula during pulmonary rehabilitation for people with chronic obstructive pulmonary disease: A systematic review and meta-analysis.

Effect of respiratory muscle training in patients with stable chronic obstructive pulmonary disease: A systematic review and meta-analysis.

Comparative Efficacy of Budesonide/Formoterol Versus Fluticasone/Salmeterol in Patients With Moderate-to-Severe Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.

Home respiratory strategies in COPD patients with chronic hypercapnic respiratory failure: a systematic review and network meta-analysis.



Mesothelioma

Evaluation of First-line and Salvage Therapies for Unresectable Malignant Mesothelioma: A Systematic Review and Network Meta-Analysis.



Artificial Intelligence

A systematic review of artificial intelligence tools for chronic pulmonary embolism on CT pulmonary angiography.

Application of machine learning for lung cancer survival prognostication-A systematic review and meta-analysis.



Smoking

Comparison of smokers' mortality with non-smokers following out-of-hospital cardiac arrests: a systematic review and meta-analysis.

Comparison of Acute Effects of E-cigarettes With and Without Nicotine and Tobacco Cigarettes on Hemodynamic and Endothelial Parameters: A Systematic Review and Meta-analysis.

Smoking on the risk of acute respiratory distress syndrome: a systematic review and meta-analysis.



Tuberculosis

(Re-)introduction of TNF antagonists and JAK inhibitors in patients with previous tuberculosis: a systematic review.

A systematic review and meta-analysis of the association between air pollutants and the incidence of tuberculosis.

The characteristics of the gut microbiota in patients with pulmonary tuberculosis: A systematic review.



Other

Effect of thoracic paravertebral nerve block on delirium in patients after video-assisted thoracoscopic surgery: a systematic review and meta-analysis of randomized controlled trials.

Risk Factors for the Development of Pneumonia in Stroke Patients: A Systematic Review and Meta-Analysis.

Association between the Quantity of Nurse-Doctor Interprofessional Collaboration and in-Patient Mortality: A Systematic Review.
EMER - the East Midlands Evidence Repository

The East Midlands Evidence Repository (EMER) is the official institutional research repository for; Derbyshire Community Health Services, Leicester Partnership Trust, NHS Nottingham and Nottinghamshire CCG, Nottinghamshire Healthcare, Sherwood Forest Hospitals, University Hospitals of Derby and Burton and the University Hospitals Of Leicester

EMER is intended to make NHS research more visible and discoverable by capturing, storing and preserving the East Midlands research output and making it available to the research community through open access protocols.

Wherever possible, full-text content is provided for all research publications in the repository. Content grows daily as new collections are added.


https://eastmid.openrepository.com/

To access full text you may have to log in to your NHS Athens account (click here to register for free). If full text is not available then please email us to request a copy.
Latest COVID-19 Articles from PubMed

Newly published and updated Guidelines and Technology Assessments from NICE

Digital technologies to deliver pulmonary rehabilitation programmes for adults with COPD: early value assessment

Gefapixant for treating refractory or unexplained chronic cough (terminated appraisal)

GaitSmart rehabilitation exercise programme for gait and mobility issues
 

The latest systematic reviews and meta-analyses from The Cochrane Library

Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings

Corticosteroids for the prevention and treatment of bronchopulmonary dysplasia: an overview of systematic reviews

Inhaled bronchodilators for the prevention and treatment of chronic lung disease in preterm infants


 
NIHR Signals

For more, see https://evidence.nihr.ac.uk/alerts/

Surgery is better than nasal sprays for people with severely blocked airways
 
Browse our Pulmonary and Respiratory Medicine online journal collection by clicking here (NHS Athens password required)



UpToDate latest information - click here 



Sign in with your NHS OpenAthens details offsite, or access onsite here.



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