Monday 27 November 2023

Respiratory Evidence Update November 2023

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Respiratory Evidence Update

27th November 2023

Contents
Leicester Publications
New & Noteworthy
East Midlands Evidence Repository
COVID-19 Updates
NICE Guidance
Cochrane Systematic Reviews
NIHR Signals
Other items of interest (including UpToDate & DynaMed)

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Leicester Publications

If any of your recently published papers are missing from this list, please let me know!
 

Evaluating niraparib versus active symptom control in patients with previously treated mesothelioma (NERO): a study protocol for a multicentre, randomised, two-arm, open-label phase II trial in UK secondary care centres.
Fennell D, Griffiths D, Eminton Z, Morgan-Fox A, Hill K, Ewings S, Stuart C, Johnson L, Mallard K, Nye M, Darlison L, Dulloo S, Cave J, Luo JL, Taylor P, Spicer J, Poile C, Bzura A, Griffiths G.

Evaluation of a COVID-19 fundamental nursing care guideline versus usual care: The COVID-NURSE cluster randomized controlled trial.
Richards DA, Bollen J, Jones B, Melendez-Torres GJ, Hulme C, Cockcroft E, Cook H, Cooper J, Creanor S, Cruickshank S, Dawe P, Doris F, Iles-Smith H, Kent M, Logan P, O'Connell A, Onysk J, Owens R, Quinn L, Rafferty AM, Romanczuk L, Russell AM, Shepherd M, Singh SJ, Sugg HVR, Coon JT, Tooze S, Warren FC, Whale B, Wootton S.

Dupilumab in type 2 airway inflammation-a step forward in targeted therapy for COPD.
Tan RVS, Aung HWW, Flynn C, Greening NJ, Brightling CE.

Perspectives of Patients With Chronic Respiratory Diseases and Medical Professionals on Pulmonary Rehabilitation in Pune, India: Qualitative Analysis.
Padhye R, Sahasrabudhe SD, Orme MW, Pina I, Dhamdhere D, Borade S, Bhakare M, Ahmed Z, Barton A, Modi M, Malcolm D, Salvi S, Singh SJ.

Enabling Adults With Severe Asthma to Exercise: A Qualitative Examination of the Challenges for Patients and Health Care Professionals.
Apps LD, Chantrell S, Majd S, Eglinton E, Singh SJ, Murphy AC, Green RH, Hudson N, Bradding P, Evans RA.

 

Search PubMed for up to date Leicester Publications

Noteworthy research

Asthma   *   Lung Cancer   *   Interstitial Lung Disease   *   Cystic Fibrosis   *   COPD   *  Smoking   *   Artificial Intelligence   *   Other 


Asthma

Systematic literature review of traits and outcomes reported in randomised controlled trials of asthma with regular dosing of inhaled corticosteroids with short-acting β2-agonist reliever, as-needed ICS/formoterol, or ICS/formoterol maintenance and reliever therapy.

Risk Factors Associated with Uncontrolled Asthma in Children- A Systematic Review and Meta-Analysis.

Efficacy and safety of biologics for oral corticosteroid-dependent asthma: A systematic review and network meta-analysis.

Best step-up treatments for children with uncontrolled asthma: A systematic review and network meta-analysis of individual participant data.


Lung Cancer
 
Thoracic day surgery versus thoracic inpatient surgery for treatment of patients with lung cancer: a systematic review and meta-analysis.

Observed and relative survival trends of lung cancer: A systematic review of population-based cancer registration data.

Chemoimmunotherapy combined with consolidative thoracic radiotherapy for extensive-stage small cell lung cancer: A systematic review and meta-analysis.

Prehabilitation programs for individuals with cancer: a systematic review of randomized-controlled trials.

Lung cancer screening program factors that influence psychosocial outcomes: A systematic review.

Long-term outcomes of robotic versus video-assisted pulmonary lobectomy for non-small cell lung cancer: systematic review and meta-analysis of reconstructed patient data.

Systematic review and meta-analysis of immune checkpoint inhibitors as single agent or in combination with chemotherapy in early-stage non-small cell lung cancer: Impact of clinicopathological factors and indirect comparison between treatment strategies.

Enhanced Patient Comfort and Satisfaction with Early Oral Feeding after Thoracoscopic Lung Cancer Resection.



Interstitial Lung Disease

Exploring the Role of Biomarkers Associated with Alveolar Damage and Dysfunction in Idiopathic Pulmonary Fibrosis-A Systematic Review.

Effect of Chest Physiotherapy on Quality of Life, Exercise Capacity and Pulmonary Function in Patients with Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis.

Heterogeneity of determining disease severity, clinical course and outcomes in systemic sclerosis-associated interstitial lung disease: a systematic literature review.


Cystic Fibrosis

Nebuliser systems for drug delivery in cystic fibrosis.



COPD

Machine learning and deep learning predictive models for long-term prognosis in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis.

Investigating the prognostic value of digital mobility outcomes in patients with chronic obstructive pulmonary disease: a systematic literature review and meta-analysis.

The Effectiveness and Safety of Long-Term Macrolide Therapy for COPD in Stable Status: A Systematic Review and Meta-Analysis.

Efficacy and Safety of Single-inhaler Triple Therapy Containing Dual Bronchodilator With Corticosteroids Compared to Monotherapy, Dual Therapy, or Open Triple Therapy in Moderate/Severe COPD: A Systematic Literature Review.

A systematic review of exercise studies for individuals hospitalized with an acute exacerbation of chronic obstructive pulmonary disease: Focus on the principles of exercise training.

Relationship between fine particulate matter (PM2.5) concentration and risk of hospitalization due to chronic obstructive pulmonary disease: a systematic review and meta-analysis.

Prevalence and clinical characteristics of sleep disorders in chronic obstructive pulmonary disease: A systematic review and meta-analysis.

High-intensity non-invasive ventilation during exercise-training versus without in people with very severe COPD and chronic hypercapnic respiratory failure: a randomised controlled trial.

Effects of pulmonary-based Qigong exercise in stable patients with chronic obstructive pulmonary disease: a randomized controlled trial.



Artificial Intelligence

Early prediction of ventilator-associated pneumonia with machine learning models: A systematic review and meta-analysis of prediction model performance✰.



Smoking

Relationship between smoking and tuberculosis recurrence: A systematic review and meta-analysis.

Effects of dulaglutide on alcohol consumption during smoking cessation.

Use of e-Cigarettes in Cigarette Smoking Cessation: Secondary Analysis of a Randomized Controlled Trial.

The effectiveness of a telephone smoking cessation program in mental health clinic patients by level of mental well-being and functioning: a secondary data analysis of a randomized clinical trial.

Effectiveness of the spirometry-based motivational intervention to quit smoking: RESET randomised trial.



Other

Extracorporeal Membrane Oxygenation Without Invasive Ventilation for Respiratory Failure in Adults: A Systematic Review.

Epidemiology of respiratory viruses among children during the SARS-CoV-2 pandemic: A systematic review and meta-analysis.

 
EMER - the East Midlands Evidence Repository

The East Midlands Evidence Repository (EMER) is the official institutional research repository for; Derbyshire Community Health Services, Leicester Partnership Trust, NHS Nottingham and Nottinghamshire CCG, Nottinghamshire Healthcare, Sherwood Forest Hospitals, University Hospitals of Derby and Burton and the University Hospitals Of Leicester

EMER is intended to make NHS research more visible and discoverable by capturing, storing and preserving the East Midlands research output and making it available to the research community through open access protocols.

Wherever possible, full-text content is provided for all research publications in the repository. Content grows daily as new collections are added.


https://eastmid.openrepository.com/

To access full text you may have to log in to your NHS Athens account (click here to register for free). If full text is not available then please email us to request a copy.
Latest COVID-19 Articles from PubMed


Asthma and COPD as co-morbidities in patients hospitalised with Covid-19 disease: a global systematic review and meta-analysis.

Nutritional Support During Long COVID: A Systematic Scoping Review.

Newly published and updated Guidelines and Technology Assessments from NICE


Extracorporeal carbon dioxide removal for acute respiratory failure

 

The latest systematic reviews and meta-analyses from The Cochrane Library


Corrector therapies (with or without potentiators) for people with cystic fibrosis with class II CFTR gene variants (most commonly F508del)

Early versus late tracheostomy in critically ill COVID‐19 patients

Interventions to prevent or cease electronic cigarette use in children and adolescents

Interventions for improving health literacy in migrants

Nebuliser systems for drug delivery in cystic fibrosis

Medically assisted hydration for adults receiving palliative care
 
NIHR Signals

For more, see https://evidence.nihr.ac.uk/alerts/

Antibiotics make little difference to children’s chest infections

Long COVID: fatigue predicts poor everyday functioning

8 findings to help you stay healthy as you age
 
Browse our Pulmonary and Respiratory Medicine online journal collection by clicking here (NHS Athens password required)



UpToDate latest information - click here 



Sign in with your NHS OpenAthens details offsite, or access onsite here.



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